Journal: The ocular surface
Article Title: Epigenetic regulation of anterior segment diseases and potential therapeutics
doi: 10.1016/j.jtos.2020.04.001
Figure Lengend Snippet: Summary of key studies pertaining to epigenetics of the anterior segment
Article Snippet: Matsuda 2015 ( 32 ) , Trabecular meshwork, glaucoma , Japan , Human , Primary culture human trabecular meshwork cells (ScienCell Research Laboratories) , , Treating cultured human TM cells with dexamethasone (to induce glaucoma) led to demethylation of promoter regions for three genes (FKBP5, ZBTB16, SCNN1A) and methylation of promoter regions for 4 genes (ARSI, HIC1, GREM2, and MATN2).
Techniques: Control, DNA Methylation Assay, Expressing, Biomarker Discovery, Methylation, Isolation, Cell Differentiation, Refractive Index, Transgenic Assay, Mutagenesis, Knock-Out, Produced, Capsules, Cell Culture, Modification, Filtration, Binding Assay, Injection, Extraction, Histone Deacetylase Assay, Irradiation, Infection, In Vitro, Dominant Negative Mutation, Transfection, Plasmid Preparation, Activity Assay, Knockdown, Sequencing, Migration, Negative Control